The main road along the coast of the Cape Range is sealed, and easily accessible to all vehicles. Some roads are 4wd only, in particular going along the coast past Yardie Creek - the sand crossing across the head of the lagoon is 4wd only, and can be inaccessible in certain tidal or flood conditions.
The east of the park is accessed by the road south of Exmouth, while to access the west side of the park and the reef, you need to drive past Exmouth and all around the cape.